Synthesis and Radioligand Binding Studies of C-5- and C-8-Substituted 1-(3,4-Dimethoxybenzyl)-2,2-dimethyl-1,2,3,4-tetrahydroisoquinoliniums as SK Channel Blockers Related to N-Methyl-laudanosine and N-Methyl-noscapine-Reference-Cited by-同舟云学术

Synthesis and Radioligand Binding Studies of C-5- and C-8-Substituted 1-(3,4-Dimethoxybenzyl)-2,2-dimethyl-1,2,3,4-tetrahydroisoquinoliniums as SK Channel Blockers Related to N-Methyl-laudanosine and N-Methyl-noscapine

Published:2005-07-01 Issue:15 Volume:48 Page:4972-4982
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Graulich Amaury¹,Scuvée-Moreau Jacqueline¹,Seutin Vincent¹,Liégeois Jean-François¹

Affiliation:

1. Laboratory of Medicinal Chemistry, Natural and Synthetic Drugs Research Center, University of Liège, avenue de l'Hôpital, 1 (B36), Laboratory of Pharmacology, Research Center for Cellular and Molecular Neurobiology, University of Liège, avenue de l'Hôpital, 3 (B23), and Laboratory of Physiology, University of Liège, avenue de l'Hôpital, 3 (B23), B-4000 Liège 1, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049025p

Reference36 articles.

1. Calcium-activated potassium channels

2. A Cyclin-Dependent Kinase-Activating Kinase (CAK) in Budding Yeast Unrelated to Vertebrate CAK

3. An apamin-sensitive Ca2+-activated K+ current in hippocampal pyramidal neurons

4. Differential Distribution of Three Ca2+-Activated K+ Channel Subunits, SK1, SK2, and SK3, in the Adult Rat Central Nervous System

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