Design and Characterization of Optimized Adenosine A2A/A1 Receptor Antagonists for the Treatment of Parkinson's Disease-Reference-Cited by-同舟云学术

Design and Characterization of Optimized Adenosine A2A/A1 Receptor Antagonists for the Treatment of Parkinson's Disease

Published:2012-01-26 Issue:3 Volume:55 Page:1402-1417
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shook Brian C.¹,Rassnick Stefanie¹,Wallace Nathaniel¹,Crooke Jeffrey¹,Ault Mark¹,Chakravarty Devraj¹,Barbay J. Kent¹,Wang Aihua¹,Powell Mark T.¹,Leonard Kristi¹,Alford Vernon¹,Scannevin Robert H.¹,Carroll Karen¹,Lampron Lisa¹,Westover Lori¹,Lim Heng-Keang¹,Russell Ronald¹,Branum Shawn¹,Wells Kenneth M.¹,Damon Sandra¹,Youells Scott¹,Li Xun¹,Beauchamp Derek A.¹,Rhodes Kenneth¹,Jackson Paul F.¹

Affiliation:

1. Janssen Research and Development, L.L.C., Welsh and McKean Roads, P.O. Box 776, Spring House, Pennsylvania 19477, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201640m

Reference69 articles.

1. New developments in understanding the etiology of Parkinson's disease and in its treatment

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3. Distribution of adenosine A2 receptor mRNA in the human brain

4. Clinical pharmacology and therapeutic use of COMT inhibition in Parkinson's disease

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