Thienoquinolines as Novel Disruptors of the PKCε/RACK2 Protein–Protein Interaction

Author:

Rechfeld Florian1,Gruber Peter1,Kirchmair Johannes23,Boehler Markus2,Hauser Nina2,Hechenberger Georg1,Garczarczyk Dorota1,Lapa Gennady B.4,Preobrazhenskaya Maria N.4,Goekjian Peter5,Langer Thierry6,Hofmann Johann1

Affiliation:

1. Biocenter, Division of Medical Biochemistry, Innsbruck Medical University, Innrain 80-82, A-6020 Innsbruck, Austria

2. Institute of Pharmacy, University of Innsbruck, Innrain 52A, 6020 Innsbruck, Austria

3. Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Vladimir-Prelog-Weg 1-5/10, 8093 Zurich, Switzerland

4. Gause Institute of New Antibiotics, Bol’shaya Pirogovskaya St. 11, 119867 Moscow, Russia

5. Laboratoire de Chimie Organique II-Glycochimie, UMR CNRS 5246 ICBMS, Université Claude Bernard—Lyon 1, Bat. 308 CPE Lyon, 43 Bd du 11 Novembre 1918, Villeurbanne Cedex, France

6. Department of Pharmaceutical Chemistry, Division of Drug Design and Medicinal Chemistry, University of Vienna, Althanstraße 14, 1090 Vienna, Austria

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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