Chemistry of Thieno [2,3-h]-/[3,2-h] Quinoline and Thieno [2,3-f]-/[3,2-f] Quinoline Derivatives Part (x), Reactivities, and Biological Activities

Author:

Gouda Moustafa A.12,Al-Hadhrami Nahlah A.3,Abu-Hashem Amin A.45,Abdelgawad Ahmed A.M.4,Salem Mohamed A.67

Affiliation:

1. Department of Chemistry, Faculty of Science and Arts, Taibah University, Ulla, Medina, Saudi Arabia

2. Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt

3. Chemistry Department, Faculty of Science, Taibah University, Medina, Saudi Arabia

4. Chemistry Departments, Faculty of Science, Jazan University, Jazan, 45142, Saudi Arabia

5. Photochemistry Department (Heterocyclic Unit), National Research Centre, Dokki, Giza, 12622, Egypt

6. Department of Chemistry, Faculty of Science & Arts, King Khalid University, Mohail Assir, KSA

7. Department of Chemistry, Faculty of Science, Al-Azhar University, Nasr, Cairo, 11284, Egypt

Abstract

Abstract: Several thieno [2,3-h] /[3,2-h] quinolines and thieno [2,3-f] /[3,2-f] quinolines (TQs) are discussed in this review from a few perspectives, including various preparation and processing methods employing cutting-edge machinery. The preparation of (TQs), from 4-(5)aminobenzothiophene, 2(3)chloromethylthiophene, 2(3)thienylboric acid, and other chemical reagents is illustrated via a number of chemical procedures in this review. The formation of (TQs) was clarified using the Michael addition, Photocyclization, Skraup reaction, Ullmann-Fetvadjian process, Suzuki-Miyaura and Sonogashira reaction, aza-Diels-Alder reaction, and Friedel-Crafts reaction.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry

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