The Synthesis of a Novel Inhibitor of B-Raf Kinase-Reference-Cited by-同舟云学术

The Synthesis of a Novel Inhibitor of B-Raf Kinase

Published:2005-12-09 Issue:1 Volume:10 Page:70-77
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Denni-Dischert Donatienne¹,Marterer Wolfgang¹,Bänziger Markus¹,Yusuff Naeem¹,Batt David¹,Ramsey Tim¹,Geng Peng¹,Michael Walter¹,Wang Run-Ming B.¹,Taplin, Francis¹,Versace Richard¹,Cesarz David¹,Perez Lawrence B.¹

Affiliation:

1. Chemical and Analytical Development, Novartis Pharma, 4002 Basel, Switzerland , and Novartis Institutes for BioMedical Research, Inc., 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, U.S.A.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op0501601

Reference18 articles.

1. Emerging Roles of Targeted Small Molecule Protein-Tyrosine Kinase Inhibitors in Cancer Therapy

2. The development of imatinib as a therapeutic agent for chronic myeloid leukemia

3. Raf kinase as a target for anticancer therapeutics

4. Mutations of the BRAF gene in human cancer

5. Selective carbon-carbon bond formation via transition metal catalysis. 3. A highly selective synthesis of unsymmetrical biaryls and diarylmethanes by the nickel- or palladium-catalyzed reaction of aryl- and benzylzinc derivatives with aryl halides

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