Discovery of Novel, Non-Peptide HIV-1 Protease Inhibitors by Pharmacophore Searching-Reference-Cited by-同舟云学术

Discovery of Novel, Non-Peptide HIV-1 Protease Inhibitors by Pharmacophore Searching

Published:1996-01-01 Issue:10 Volume:39 Page:2047-2054
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Shaomeng¹,Milne G. W. A.¹,Yan Xinjian¹,Posey Isadora J.¹,Nicklaus Marc C.¹,Graham Lisa¹,Rice William G.¹

Affiliation:

1. Laboratory of Medicinal Chemistry, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-4255, Department of Chemistry, University of the District of Columbia, Washington, D.C. 20008, and Laboratory of Antiviral Drug Mechanisms, SAIC Frederick, NCI-Frederick Cancer Research and Development Center, Frederick, Maryland 21702-1201

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm950874%2B

Reference36 articles.

1. Isolation of Human T-Cell Leukemia Virus in Acquired Immune Deficiency Syndrome (AIDS)

2. Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

3. Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

4. Human immunodeficiency virus has an aspartic-type protease that can be inhibited by pepstatin A.

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