2-Hexylthio-β,γ-CH2-ATP is an Effective and Selective NTPDase2 Inhibitor-Reference-Cited by-同舟云学术

2-Hexylthio-β,γ-CH2-ATP is an Effective and Selective NTPDase2 Inhibitor

Published:2014-07-14 Issue:14 Volume:57 Page:5919-5934
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gillerman Irina¹,Lecka Joanna²³,Simhaev Luba¹,Munkonda Mercedes N.²³,Fausther Michel²³,Martín-Satué Mireia²³⁴,Senderowitz Hanoch¹,Sévigny Jean²³,Fischer Bilha¹

Affiliation:

1. Department of Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel

2. Département de microbiologie-infectiologie et d’immunologie, Faculté de Médecine, Université Laval, Québec City, Québec, Canada

3. Centre de recherche du CHU de Québec, Québec City, Québec, Canada

4. Department of Pathology and Experimental Therapeutics, University of Barcelona, Barcelona, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401933c

Reference62 articles.

1. Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

2. Cellular function and molecular structure of ecto-nucleotidases

3. Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8

4. 5′-Nucleotidase: molecular structure and functional aspects

5. Capillary electrophoresis-based nanoscale assays for monitoring ecto-5′-nucleotidase activity and inhibition in preparations of recombinant enzyme and melanoma cell membranes

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Platelets isolation and ectonucleotidase assay: Revealing functional aspects of the communication between the vasculature and the immune system;Journal of Immunological Methods;2024-10

2. Ectonucleotidase inhibitors: targeting signaling pathways for therapeutic advancement—an in-depth review;Purinergic Signalling;2024-07-03

3. Double-modified, thio and methylene ATP analogue facilitates wound healing in vitro and in vivo;Scientific Reports;2024-06-07

4. Chemo-enzymatic production of base-modified ATP analogues for polyadenylation of RNA;Chemical Science;2024

5. Synthesis, characterization and biological evaluation of thiadiazole amide derivatives as nucleoside triphosphate diphosphohydrolases (NTPDases) inhibitors;Bioorganic Chemistry;2022-01