Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design
Author:
Affiliation:
1. Sunesis Pharmaceuticals, Inc., 341 Oyster Point Boulevard, South San Francisco, California 94080
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm020230j
Reference49 articles.
1. Cysteine Proteases and Their Inhibitors
2. Protease Inhibitors: Current Status and Future Prospects
3. Caspases as Targets for Anti-Inflammatory and Anti-Apoptotic Drug Discovery
4. A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes
5. Caspases: key mediators of apoptosis
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