Preparation of Substituted Piperazinones via Tandem Reductive Amination−(N,N‘-Acyl Transfer)−Cyclization
Author:
Affiliation:
1. Department of Medicinal Chemistry, Merck Research Laboratories, West Point, Pennsylvania 19486
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol025644l
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1. Preparation of Optically Active Piperazines from Ethyl (S)-2-(2-Alkyl-1-aziridinyl)acetates
2. Praziquantel Analogues. I. New and Short Synthesis of 2-Acyl-4-oxo-1,2,3,4,6,7,12,12b-octahydropyrazino[1',2':1,2]pyrido[3,4-b]indoles
3. Non-peptide glycoprotein IIb/IIIa inhibitors. 6. Design and synthesis of rigid, centrally constrained non-peptide fibrinogen receptor antagonists
4. Efficient synthesis of substituted piperazinones via tandem reductive amination–cyclization
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