A Medicinal Chemistry-Driven Approach Identified the Sterol Isomerase EBP as the Molecular Target of TASIN Colorectal Cancer Toxins
Author:
Funder
National Cancer Institute
Welch Foundation
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.9b13407
Reference19 articles.
1. Identification and characterization of the familial adenomatous polyposis coli gene
2. Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein.
3. Molecular Diagnosis of Familial Adenomatous Polyposis
4. Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene
5. Selective targeting of mutant adenomatous polyposis coli ( APC ) in colorectal cancer
Cited by 23 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Patent highlights December 2023–January 2024;Pharmaceutical Patent Analyst;2024-09-04
2. High expression of EBP is an adverse prognostic factor for de novo acute myeloid leukemia;Hematology;2024-08
3. Variation in bile acid synthesis capacity: A key factor leading to different lipid deposition patterns in goldfish breeds;Aquaculture Reports;2024-08
4. Discovery and Optimization of N-Arylated Tetracyclic Dicarboximides That Target Primary Glioma Stem-like Cells;Journal of Medicinal Chemistry;2024-05-28
5. Chemical Inhibition of Sterol Biosynthesis;Biomolecules;2024-03-28
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3