Enantiodivergent Formation of C–P Bonds: Synthesis of P-Chiral Phosphines and Methylphosphonate Oligonucleotides-Reference-Cited by-同舟云学术

Enantiodivergent Formation of C–P Bonds: Synthesis of P-Chiral Phosphines and Methylphosphonate Oligonucleotides

Published:2020-02-28 Issue:12 Volume:142 Page:5785-5792
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Xu Dongmin¹,Rivas-Bascón Nazaret¹,Padial Natalia M.¹^ORCID,Knouse Kyle W.¹^ORCID,Zheng Bin²^ORCID,Vantourout Julien C.¹^ORCID,Schmidt Michael A.²^ORCID,Eastgate Martin D.²^ORCID,Baran Phil S.¹^ORCID

Affiliation:

1. Department of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States

2. Chemistry Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States

Funder

Universidad de Granada

H2020 Marie Sklodowska-Curie Actions

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.9b13898

Reference39 articles.

1. Über optisch‐aktive Verbindungen des Phosphors

2. Electronic Structures of LNA Phosphorothioate Oligonucleotides

3. Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides

4. Unlocking P(V): Reagents for chiral phosphorothioate synthesis

5. Methylphosphonate mapping of phosphate contacts critical for RNA recognition by the human immunodeficiency virus tat and rev proteins

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