Bactericidal Activity Engineered on Human Pancreatic Ribonuclease and Onconase
Author:
Affiliation:
1. Laboratori d’Enginyeria de Proteïnes, Departament de Biologia, Facultat de Ciències, Universitat de Girona, Campus de Montilivi s/n 17071 Girona, Spain, and Institut d’Investigació Biomèdica de Girona Josep Trueta, Girona, Spain
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp8001914
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2. Ribonuclease A variants with potent cytotoxic activity
3. Endowing Human Pancreatic Ribonuclease with Toxicity for Cancer Cells
4. A Nuclear Localization Sequence Endows Human Pancreatic Ribonuclease with Cytotoxic Activity
5. Disruption of Shape-Complementarity Markers to Create Cytotoxic Variants of Ribonuclease A
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