Conformational Preferences of Natural and C3-Modified Epothilones in Aqueous Solution-Reference-Cited by-同舟云学术

Conformational Preferences of Natural and C3-Modified Epothilones in Aqueous Solution

Published:2008-02-14 Issue:5 Volume:51 Page:1469-1473
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Erdélyi Máté¹,Pfeiffer Bernhard¹,Hauenstein Kurt¹,Fohrer Jörg¹,Gertsch Jürg¹,Altmann Karl-Heinz¹,Carlomagno Teresa¹

Affiliation:

1. Max-Planck-Institute for Biophysical Chemistry, NMR-Based Structural Biology, Am Fassberg 11, D-37077 Göttingen, Germany, and ETH Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, HCI H 405, Wolfgang Pauli Str. 10, CH-8093 Zürich, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm7013452

Reference41 articles.

1. Recent Developments in the Chemical Biology of Epothilones

2. bHöfle, G.; Reichenbach, H.InAnticancer Agents form Natural Products;Cragg, G. M.; Kingston, D. G. I.; Newman, D. J., Eds.Taylor & Francis:Boca Raton, FL,2005; Vol.41, pp3–450.

3. Microtubules as a target for anticancer drugs

4. Activities of the Microtubule-stabilizing Agents Epothilones A and B with Purified Tubulin and in Cells Resistant to Paclitaxel (Taxol®)

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