Solution-State Preorganization of Cyclic β-Hairpin Ligands Determines Binding Mechanism and Affinities for MDM2
Author:
Affiliation:
1. Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, United States
2. Department of Chemistry—BMC, Uppsala University, SE-75123 Uppsala, Sweden
Funder
Vetenskapsr?det
NIH Office of the Director
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.1c00029
Reference94 articles.
1. Crystal Structures of Protein-Bound Cyclic Peptides
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4. Targeting intracellular protein–protein interactions with cell-permeable cyclic peptides
5. Molecular Simulation of Conformational Pre-Organization in Cyclic RGD Peptides
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