A Novel Series of Highly Potent 2,6,9-Trisubstituted Purine Cyclin-Dependent Kinase Inhibitors-Reference-Cited by-同舟云学术

A Novel Series of Highly Potent 2,6,9-Trisubstituted Purine Cyclin-Dependent Kinase Inhibitors

Published:2013-07-24 Issue:15 Volume:56 Page:6234-6247
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gucký Tomáš¹,Jorda Radek²,Zatloukal Marek¹,Bazgier Václav¹³,Berka Karel³,Řezníčková Eva²,Béres Tibor¹,Strnad Miroslav²,Kryštof Vladimír²

Affiliation:

1. Centre of the Region Haná for Biotechnological and Agricultural Research, Department of Growth Regulators, Faculty of Science, Palacký University, Šlechtitelů 11, 78371 Olomouc, Czech Republic

2. Laboratory of Growth Regulators, Faculty of Science, Palacký University & Institute of Experimental Botany ASCR, Šlechtitelů 11, 78371 Olomouc, Czech Republic

3. Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University Olomouc, 17 Listopadu 12, 77146 Olomouc, Czech Republic

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm4006884

Reference56 articles.

1. Mammalian cyclin-dependent kinases

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4. Cytokinin-Derived Cyclin-Dependent Kinase Inhibitors: Synthesis and cdc2 Inhibitory Activity of Olomoucine and Related Compounds

5. Pharmacodynamic Effects of Seliciclib, an Orally Administered Cell Cycle Modulator, in Undifferentiated Nasopharyngeal Cancer

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