Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-<i>b</i>]pyridazine Derivatives Identified by Scaffold Hopping-Reference-Cited by-同舟云学术

Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping

Published:2023-08-03 Issue:16 Volume:66 Page:11133-11157
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Břehová Petra¹^ORCID,Řezníčková Eva²^ORCID,Škach Kryštof¹^ORCID,Jorda Radek²^ORCID,Dejmek Milan¹^ORCID,Vojáčková Veronika²^ORCID,Šála Michal¹,Kovalová Markéta²,Dračínský Martin¹,Dolníková Alexandra³,Strmeň Timotej¹,Kinnertová Monika²,Chalupský Karel¹,Dvořáková Alexandra¹,Gucký Tomáš²,Mertlíková Kaiserová Helena¹,Klener Pavel³,Nencka Radim¹,Kryštof Vladimír²⁴^ORCID

Affiliation:

1. Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, 16000 Prague, Czech Republic

2. Department of Experimental Biology, Faculty of Science, Palacký University Olomouc, Šlechtitelů 27, 78371 Olomouc, Czech Republic

3. Institute of Pathological Physiology, First Faculty of Medicine, Charles University, 12108 Prague, Czech Republic

4. Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc, Hněvotínská 5, 77900 Olomouc, Czech Republic

Funder

European Commission

GrantovÃ¡ Agentura CeskÃ© Republiky

Akademie Ved CeskÃ© Republiky

Univerzita PalackÃ©ho v Olomouci

Ministerstvo ZdravotnictvÃ CeskÃ© Republiky

Univerzita Karlova v Praze

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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