Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents-Reference-Cited by-同舟云学术

Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents

Published:2009-06-24 Issue:14 Volume:52 Page:4288-4305
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Huang Kenneth H.¹,Veal James M.¹,Fadden R. Patrick¹,Rice John W.¹,Eaves Jeron¹,Strachan Jon-Paul¹,Barabasz Amy F.¹,Foley Briana E.¹,Barta Thomas E.¹,Ma Wei¹,Silinski Melanie A.¹,Hu Mei¹,Partridge Jeffrey M.¹,Scott Anisa¹,DuBois Laura G.¹,Freed Tiffany¹,Steed Paul M.¹,Ommen Andy J.¹,Smith Emilie D.¹,Hughes Philip F.¹,Woodward Angela R.¹,Hanson Gunnar J.¹,McCall W. Stephen¹,Markworth Christopher J.¹,Hinkley Lindsay¹,Jenks Matthew¹,Geng Lifeng¹,Lewis Meredith¹,Otto James¹,Pronk Bert¹,Verleysen Katleen¹,Hall Steven E.¹

Affiliation:

1. Serenex Inc., 323 Foster Street, Durham, North Carolina 27701

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900230j

Reference64 articles.

1. HSP90 as a new therapeutic target for cancer therapy: the story unfolds

2. Inhibitors of HSP90 and other chaperones for the treatment of cancer

3. Heat shock protein 90 as a molecular target for cancer therapeutics