Discovery of Selective Small Molecule ROMK Inhibitors as Potential New Mechanism Diuretics-Reference-Cited by-同舟云学术

Discovery of Selective Small Molecule ROMK Inhibitors as Potential New Mechanism Diuretics

Published:2012-04-13 Issue:5 Volume:3 Page:367-372
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Tang Haifeng¹,Walsh Shawn P.¹,Yan Yan¹,de Jesus Reynalda K.¹,Shahripour Aurash¹,Teumelsan Nardos¹,Zhu Yuping¹,Ha Sookhee¹,Owens Karen A.¹,Thomas-Fowlkes Brande S.¹,Felix John P.¹,Liu Jessica¹,Kohler Martin¹,Priest Birgit T.¹,Bailey Timothy¹,Brochu Richard¹,Alonso-Galicia Magdalena¹,Kaczorowski Gregory J.¹,Roy Sophie¹,Yang Lihu¹,Mills Sander G.¹,Garcia Maria L.¹,Pasternak Alexander¹

Affiliation:

1. Departments of †Medicinal Chemistry, ‡Hypertension, §Ion Channels, ⊥Preclinical DMPK, and ¶Chemistry Modeling, Merck Research Laboratories, Rahway New Jersey 07065, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml3000066

Reference20 articles.

1. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood PressureThe JNC 7 Report

2. Combination therapy for the management of hypertension: A review of the evidence

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4. Evidence for the efficacy of low-dose diuretic monotherapy

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