Identification of Novel Non-Hydroxamate Anthrax Toxin Lethal Factor Inhibitors by Topomeric Searching, Docking and Scoring, and in Vitro Screening-Reference-Cited by-同舟云学术

Identification of Novel Non-Hydroxamate Anthrax Toxin Lethal Factor Inhibitors by Topomeric Searching, Docking and Scoring, and in Vitro Screening

Published:2009-11-20 Issue:12 Volume:49 Page:2726-2734
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Chiu Ting-Lan¹,Solberg Jonathan¹,Patil Satish¹,Geders Todd W.¹,Zhang Xia¹,Rangarajan Subhashree¹,Francis Rawle¹,Finzel Barry C.¹,Walters Michael A.¹,Hook Derek J.¹,Amin Elizabeth A.¹

Affiliation:

1. Department of Medicinal Chemistry, College of Pharmacy, Institute for Therapeutics Discovery and Development, and Minnesota Supercomputing Institute for Advanced Computational Research, University of Minnesota, 717 Delaware Street Southeast, Minneapolis, Minnesota 55414-2959 and Department of Chemistry, University of Minnesota, 207 Pleasant Street Southeast, Minneapolis, Minnesota 55455-0431

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci900186w

Reference65 articles.

1. Contribution of individual toxin components to virulence of Bacillus anthracis

2. Anthrax Lethal Factor Proteolysis and Inactivation of MAPK Kinase

3. Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor

4. Discovery and Development of Anthrax Lethal Factor Metalloproteinase Inhibitors

5. Inhibitors of anthrax lethal factor

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