Activity-Based Hydrazine Probes for Protein Profiling of Electrophilic Functionality in Therapeutic Targets-Reference-Cited by-同舟云学术

Activity-Based Hydrazine Probes for Protein Profiling of Electrophilic Functionality in Therapeutic Targets

Published:2021-08-19 Issue:9 Volume:7 Page:1524-1534
ISSN:2374-7943
Container-title:ACS Central Science
language:en
Short-container-title:ACS Cent. Sci.

Author:

Lin Zongtao¹,Wang Xie¹^ORCID,Bustin Katelyn A.¹^ORCID,Shishikura Kyosuke¹,McKnight Nate R.¹,He Lin²^ORCID,Suciu Radu M.³,Hu Kai⁴,Han Xian⁵,Ahmadi Mina¹,Olson Erika J.³,Parsons William H.⁶^ORCID,Matthews Megan L.¹^ORCID

Affiliation:

1. Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

2. Zenagem, LLC, Fountain Valley, California 92708, United States

3. Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States

4. Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States

5. Department of Structural Biology, St. Jude Children’s Research Hospital, Memphis, Tennessee 38105, United States

6. Department of Chemistry and Biochemistry, Oberlin College, Oberlin, Ohio 44074, United States

Funder

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscentsci.1c00616

Reference56 articles.

1. Enzyme Inhibitor Discovery by Activity-Based Protein Profiling

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5. Discovery of small-molecule enzyme activators by activity-based protein profiling

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