High-Performance Genetically Encoded Green Fluorescent Biosensors for Intracellular l-Lactate

Author:

Hario Saaya1,Le Giang N. T.12,Sugimoto Hikaru3,Takahashi-Yamashiro Kei45,Nishinami Suguru6,Toda Hirofumi6,Li Selene1,Marvin Jonathan S.7ORCID,Kuroda Shinya8,Drobizhev Mikhail9,Terai Takuya1ORCID,Nasu Yusuke110ORCID,Campbell Robert E.1511ORCID

Affiliation:

1. Department of Chemistry, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan

2. Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada

3. Department of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan

4. Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan

5. Department of Chemistry, Faculty of Science, University of Alberta, Edmonton, Alberta T6G 2G2, Canada

6. International Institute for Integrative Sleep Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan

7. Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, Virginia 20147, United States

8. Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan

9. Department of Microbiology and Cell Biology, Montana State University, Bozeman, Montana 59717, United States

10. PRESTO, Japan Science and Technology Agency, Chiyoda-ku, Tokyo 102-0075, Japan

11. CERVO Brain Research Center and Department of Biochemistry, Microbiology, and Bioinformatics, Université Laval, Québec, Québec G1 V 0A6, Canada

Funder

Ministry of Education, Culture, Sports, Science and Technology

Publisher

American Chemical Society (ACS)

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