An HR2-Mimicking Sulfonyl-γ-AApeptide Is a Potent Pan-coronavirus Fusion Inhibitor with Strong Blood–Brain Barrier Permeability, Long Half-Life, and Promising Oral Bioavailability-Reference-Cited by-同舟云学术

An HR2-Mimicking Sulfonyl-γ-AApeptide Is a Potent Pan-coronavirus Fusion Inhibitor with Strong Blood–Brain Barrier Permeability, Long Half-Life, and Promising Oral Bioavailability

Published:2023-04-28 Issue:5 Volume:9 Page:1046-1058
ISSN:2374-7943
Container-title:ACS Central Science
language:en
Short-container-title:ACS Cent. Sci.

Author:

Xue Songyi¹,Xu Wei²,Wang Lei¹,Wang Xinling²,Duan Qianyu²,Calcul Laurent¹,Wang Shaohui³,Liu Wenqi¹^ORCID,Sun Xingmin³,Lu Lu²,Jiang Shibo²^ORCID,Cai Jianfeng¹^ORCID

Affiliation:

1. Department of Chemistry, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620, United States

2. Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microbes and Infection, Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200433, China

3. Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33620, United States

Funder

University of South Florida

Ministry of Science and Technology of the People's Republic of China

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscentsci.3c00313