Click Chemistry Selectively Activates an Auristatin Protodrug with either Intratumoral or Systemic Tumor-Targeting Agents-Reference-Cited by-同舟云学术

Click Chemistry Selectively Activates an Auristatin Protodrug with either Intratumoral or Systemic Tumor-Targeting Agents

Published:2023-06-22 Issue:7 Volume:9 Page:1400-1408
ISSN:2374-7943
Container-title:ACS Central Science
language:en
Short-container-title:ACS Cent. Sci.

Author:

McFarland Jesse M.¹^ORCID,Alečković Maša¹,Coricor George¹,Srinivasan Sangeetha¹,Tso Matthew¹,Lee John¹,Nguyen Tri-Hung¹,Mejía Oneto José M.¹

Affiliation:

1. Shasqi Inc., 665 3rd St, Suite 501, San Francisco, California 94107, United States

Funder

Shasqi, Inc.

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscentsci.3c00365

Reference56 articles.

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2. The Royal Swedish Academy of Sciences. Click chemistry and bioorthogonal chemistry. The Noble Prize Committee of Chemistry. 5 October 2022. Available at: https://www.nobelprize.org/uploads/2022/10/advanced-chemistryprize2022-2.pdf. Accessed 20 May 2023.

3. Click activated protodrugs against cancer increase the therapeutic potential of chemotherapy through local capture and activation

4. Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

5. Implantable biomaterial based on click chemistry for targeting small molecules

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