Click activated protodrugs against cancer increase the therapeutic potential of chemotherapy through local capture and activation-Reference-Cited by-同舟云学术

Click activated protodrugs against cancer increase the therapeutic potential of chemotherapy through local capture and activation

Published:2021 Issue:4 Volume:12 Page:1259-1271
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Wu Kui¹²³⁴,Yee Nathan A.⁵⁶⁴,Srinivasan Sangeetha⁵⁶⁴,Mahmoodi Amir⁵⁶⁴,Zakharian Michael⁵⁶⁴,Mejia Oneto Jose M.⁵⁶⁴,Royzen Maksim¹²³⁴^ORCID

Affiliation:

1. University at Albany

2. SUNY

3. Albany

4. USA

5. Shasqi, Inc.

6. San Francisco

Abstract

The Click Activated Protodrugs Against Cancer (CAPAC) platform uses click chemistry to activate cytotoxic drugs directly at a target site with minimal toxicity, overcoming limitations of conventional chemotherapy and traditional targeted therapies.

Funder

Division of Chemistry

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D0SC06099B

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