Synthesis of <i>gem</i>-Difluorinated 2,3-Dihydrobenzofurans Using Freon-22 via [4 + 1] Annulation of Difluorocarbene and Antitumor Activity Evaluation-Reference-Cited by-同舟云学术

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Synthesis of gem-Difluorinated 2,3-Dihydrobenzofurans Using Freon-22 via [4 + 1] Annulation of Difluorocarbene and Antitumor Activity Evaluation

Published:2024-02-01 Issue:6 Volume:26 Page:1212-1217
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Zhou Qianying¹²,Huang Mi³^ORCID,Shen Yongcun¹,Chen Zhenling⁴,Xu Liying²,Yang Zhigang²^ORCID

Affiliation:

1. School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan 430070, China

2. Department of Radiology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China

3. Department of Clinical Sciences, Clinical Research Centre, Lund University, 21428 Malmö, Sweden

4. School of Chemical Engineering, Guizhou Institute of Technology, Guiyang 550003, China

Funder

National Key Research and Development Program of China

Natural Science Foundation of Hubei Province

Academic New Seedling Plan Project of Guizhou Institute of Technology

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.4c00011

Reference33 articles.

1. aUneyama, K. Organofluorine Chemistry; Wiley-Blackwell: New Delhi, 2006; pp 1–100.

2. Organic fluorine compounds: a great opportunity for enhanced materials properties

3. 4′-Fluoro-nucleosides and nucleotides: from nucleocidin to an emerging class of therapeutics

4. Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

5. The unique fluorine effects in organic reactions: recent facts and insights into fluoroalkylations

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1. Silver‐Catalyzed Carbofluorination of Olefins and α‐Fluoroolefins with Carbamoyl Radicals;Chemistry – A European Journal;2024-06-18

2. Base-controlled selective cleavage of the C–F bond of difluorocarbene for the divergent assembly of indolizines;Organic Chemistry Frontiers;2024

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