Base-controlled selective cleavage of the C–F bond of difluorocarbene for the divergent assembly of indolizines-Reference-Cited by-同舟云学术

Base-controlled selective cleavage of the C–F bond of difluorocarbene for the divergent assembly of indolizines

Published:2024 Issue:15 Volume:11 Page:4214-4218
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wu Chun-Yan¹,Chen Xiang-Long¹^ORCID,Yang Dong-Sheng¹,Tang Yong-Xing¹,Wang Li-Sheng¹,Wu Yan-Dong¹,Zhuang Shi-Yi²,Wu An-Xin¹³^ORCID

Affiliation:

1. National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, China

2. Key Laboratory of Specialty Agri-product Quality and Hazard Controlling Technology of Zhejiang Province, College of Life Sciences, China Jiliang University, Hangzhou 310018, P. R. China

3. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000 P. R. China

Abstract

A [3 + 1 + 1] cascade annulation reaction for the divergent construction of trisubstituted indolizines using sulfoxonium ylides, BrCF2CO2Me and pyridinium salts as readily available substrates has been developed.

Funder

National Natural Science Foundation of China

Higher Education Discipline Innovation Project

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO00801D

Reference43 articles.

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4. Fluorinated Ylides/Carbenes and Related Intermediates from Phosphonium/Sulfonium Salts

5. Difluorocarbene as a Building Block for Consecutive Bond-Forming Reactions