Two-Step Synthesis of 3,4-Dihydropyrrolopyrazinones from Ketones and Piperazin-2-ones-Reference-Cited by-同舟云学术

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Two-Step Synthesis of 3,4-Dihydropyrrolopyrazinones from Ketones and Piperazin-2-ones

Published:2018-02-06 Issue:4 Volume:20 Page:1252-1255
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Sandoval Cosme¹,Lim Ngiap-Kie¹,Zhang Haiming¹^ORCID

Affiliation:

1. Department of Small Molecule Process Chemistry, Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.8b00197

Reference43 articles.

1. aWard, R. A.; Jones, C. D.; Feron, J. L.PCT Int. Appl. 2017080980, 2017.

2. bWard, R. A.; Graham, M. A.; Swallow, S.; Jones, C. D.PCT Int. Appl. 2016162325, 2016.

3. cMirizzi, D.; Cervi, G.; D’Anello, M.; Papeo, G. M. E.; Ferguson, R.; Casuscelli, F.PCT Int. Appl. 2010031816, 2010.

4. dZhao, G.U.S. Patent Appl. 20070185097, 2007.

5. Discovery of Potent and Selective Tricyclic Inhibitors of Bruton’s Tyrosine Kinase with Improved Druglike Properties

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