Bond-Breaking Bio-orthogonal Chemistry Efficiently Uncages Fluorescent and Therapeutic Compounds under Physiological Conditions
Author:
Affiliation:
1. Department of Chemistry, University at Albany,, 1400 Washington Avenue, Albany, New York 12222, United States
Funder
National Cancer Institute
National Science Foundation
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.0c02129
Reference23 articles.
1. Carboxylesterases - Detoxifying Enzymes and Targets for Drug Therapy
2. Enzymes involved in the bioconversion of ester-based prodrugs
3. Enhanced Antitumor Activity of Monophosphate Ester Prodrugs of Gemcitabine: In Vitro and In Vivo Evaluation
4. Chemically triggered drug release from an antibody-drug conjugate leads to potent antitumour activity in mice
5. Diels-Alder reaction–triggered bioorthogonal protein decaging in living cells
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Reversible RNA Acylation Using Bio-Orthogonal Chemistry Enables Temporal Control of CRISPR-Cas9 Nuclease Activity;ACS Chemical Biology;2024-07-25
2. Bioorthogonal Bond Cleavage Chemistry for On-demand Prodrug Activation: Opportunities and Challenges;Journal of Medicinal Chemistry;2023-12-12
3. Click chemistry and drug delivery: A bird's-eye view;Acta Pharmaceutica Sinica B;2022-10
4. Mutual leveraging of proximity effects and click chemistry in chemical biology;Medicinal Research Reviews;2022-09-29
5. On-Demand Activation of a Bioorthogonal Prodrug of SN-38 with Fast Reaction Kinetics and High Releasing Efficiency In Vivo;Journal of Medicinal Chemistry;2021-12-29
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3