Enhanced Antitumor Activity of Monophosphate Ester Prodrugs of Gemcitabine: In Vitro and In Vivo Evaluation

Author:

Qi Huixin,Lu Jia,Li Jiajun,Wang Meiyu,Xu Yunting,Wang Yedong,Zhang Hongjian

Funder

Soochow University

Chinese National Science Foundation

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference22 articles.

1. Clinical pharmacology and pharmacogenetics of gemcitabine;Wong;Drug Metab Rev,2009

2. Metabolism and disposition of gemcitabine, and oncolytic deoxycytidine analog, in mice, rats, and dogs;Shipley;Drug Metab Dispos,1992

3. Gemcitabine: metabolism, mechanisms of action, and self-potentiation;Plunkett;Semin Oncol,1995

4. Gemcitabine-loaded liposomes: rationale, potentialities and future perspectives;Federico;Int J Nanomedicine,2012

5. Gemcitabine versus modified gemcitabine: a review of several promising chemical modifications;Moysan;Mol Pharm,2013

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