Combining (CH2O)n and (NH4)2CO3 as a Formamidine Equivalent for “Four-in-One” Synthesis of Fluoroalkylated 2-H-Pyrimidines-Reference-Cited by-同舟云学术

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Combining (CH₂O)_n and (NH₄)₂CO₃ as a Formamidine Equivalent for “Four-in-One” Synthesis of Fluoroalkylated 2-H-Pyrimidines

Published:2024-08-09 Issue:33 Volume:26 Page:7078-7082
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Han Wei¹,Ren Yuan-Yuan¹,Tang Ming-Yao¹,Ji Yi-Fan¹,Ge Danhua¹^ORCID,Ma Mengtao²^ORCID,Shen Zhi-Liang¹^ORCID,Chu Xue-Qiang¹^ORCID

Affiliation:

1. Technical Institute of Fluorochemistry, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China

2. Department of Chemistry and Materials Science, College of Science, Nanjing Forestry University, Nanjing 210037, China

Funder

Nanjing Tech University

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.4c02785

Reference40 articles.

1. Therapeutic potential of heterocyclic pyrimidine scaffolds

2. Rings in Clinical Trials and Drugs: Present and Future

3. A deconstruction–reconstruction strategy for pyrimidine diversification

4. C2-Selective, Functional-Group-Divergent Amination of Pyrimidines by Enthalpy-Controlled Nucleophilic Functionalization

5. Skeletal Editing of Pyrimidines to Pyrazoles by Formal Carbon Deletion

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