Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides-Reference-Cited by-同舟云学术

Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides

Published:2016-06-13 Issue:13 Volume:18 Page:3082-3085
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Huang Wen-Xue¹²,Liu Lian-Jin¹,Wu Bo¹,Feng Guang-Shou¹,Wang Baomin²,Zhou Yong-Gui¹

Affiliation:

1. State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, P. R. China

2. State Key Laboratory of Fine Chemicals, School of Pharmaceutical Science and Technology, Dalian University of Technology, 2 Linggong Road, Dalian 116024, P. R. China

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.6b01190

Reference56 articles.

1. Dragmacidin, a new cytotoxic bis(indole) alkaloid from a deep water marine sponge, Dragmacidon sp

2. Discovery Process and Pharmacological Characterization of 2-(S)-(4-Fluoro-2-methylphenyl)piperazine-1-carboxylic Acid [1-(R)-(3,5-Bis-trifluoromethylphenyl)ethyl]methylamide (Vestipitant) as a Potent, Selective, and Orally Active NK1Receptor Antagonist

3. L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor