Design, Synthesis, and Characterization of SO2-Containing Azabicyclo[3.n.1]alkanes: Promising Building Blocks for Drug Discovery-Reference-Cited by-同舟云学术

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Design, Synthesis, and Characterization of SO2-Containing Azabicyclo[3.n.1]alkanes: Promising Building Blocks for Drug Discovery

Published:2015-03-31 Issue:8 Volume:17 Page:1922-1925
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Druzhenko Tetiana¹²,Denisenko Olexandr¹,Kheylik Yuri¹,Zozulya Sergey¹,Shishkina Svitlana S.³,Tolmachev Andrei¹²,Mykhailiuk Pavel K.¹²

Affiliation:

1. Enamine, Ltd., Chervonotkatska 78, Kyiv 01103, Ukraine

2. Department of Chemistry, National Taras Shevchenko University of Kyiv, Volodymyrska 64, Kyiv 01033, Ukraine

3. STC ‘Institute for Single Crystals’, NAS of Ukraine 60 Lenina Avenue, Kharkiv 61001, Ukraine

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.5b00608

Reference40 articles.

1. Scaffold hopping

2. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

3. Conformational Restriction and/or Steric Hindrance in Medicinal Chemistry

4. Designing novel building blocks is an overlooked strategy to improve compound quality

5. New and unusual scaffolds in medicinal chemistry

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