Isolation of a Metabolite from the pks Island Provides Insights into Colibactin Biosynthesis and Activity-Reference-Cited by-同舟云学术

Isolation of a Metabolite from the pks Island Provides Insights into Colibactin Biosynthesis and Activity

Published:2015-03-10 Issue:6 Volume:17 Page:1545-1548
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Brotherton Carolyn A.¹,Wilson Matthew¹,Byrd Gary²,Balskus Emily P.¹

Affiliation:

1. Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States

2. Small Molecule Mass Spectrometry Facility, Faculty of Arts and Sciences Division of Science, Harvard University, Cambridge, Massachusetts 02138, United States

Funder

David and Lucile Packard Foundation

Damon Runyon Cancer Research Foundation

Richard and Susan Smith Family Foundation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.5b00432

Reference20 articles.

1. Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells

2. Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells

3. Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

4. The genus P seudovibrio contains metabolically versatile bacteria adapted for symbiosis

5. Gut Symbionts from Distinct Hosts Exhibit Genotoxic Activity via Divergent Colibactin Biosynthesis Pathways

Cited by 60 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Rapid Synthesis of Colibactin Warhead Model Compounds Using New Metal‐Free Photocatalytic Cyclopropanation Reactions Facilitates the Investigation of Biological Mechanisms;Chemistry – A European Journal;2023-09-07

2. Structure Elucidation of Secondary Metabolites: Current Frontiers and Lingering Pitfalls;Accounts of Chemical Research;2023-05-23

3. A small molecule inhibitor prevents gut bacterial genotoxin production;Nature Chemical Biology;2022-10-17

4. The microbiome-product colibactin hits unique cellular targets mediating host–microbe interaction;Frontiers in Pharmacology;2022-09-12

5. Characterization of genotoxin-encoding Escherichia coli isolated from specific-pathogen free cats with impaired fertility;Veterinary Microbiology;2022-03