Access to a Catalytically Generated Umpolung Reagent through the Use of Cu-Catalyzed Reductive Coupling of Ketones and Allenes for the Synthesis of Chiral Vicinal Aminoalcohol Synthons-Reference-Cited by-同舟云学术

Access to a Catalytically Generated Umpolung Reagent through the Use of Cu-Catalyzed Reductive Coupling of Ketones and Allenes for the Synthesis of Chiral Vicinal Aminoalcohol Synthons

Published:2019-11-26 Issue:23 Volume:21 Page:9753-9758
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Gargaro Samantha L.¹^ORCID,Klake Raphael K.¹^ORCID,Burns Kevin L.¹,Elele Sharon O.¹,Gentry Skyler L.¹,Sieber Joshua D.¹^ORCID

Affiliation:

1. Department of Chemistry, Virginia Commonwealth University, 1001 West Main Street, Richmond, Virginia 23284-3028, United States

Funder

Bill and Melinda Gates Foundation

Virginia Commonwealth University

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.orglett.9b03937

Reference56 articles.

1. Natural Products with Heteroatom-Rich Ring Systems

2. Biocatalytic approaches towards the stereoselective synthesis of vicinal amino alcohols

3. Cheminformatic Analysis of Natural Products and their Chemical Space

4. Multi-step synthesis strategies towards 1,2-amino alcohols with special emphasis on phenylpropanolamines

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