Mild and Diazo-Free Synthesis of Trifluoromethyl-Cyclopropanes Using Sulfonium Ylides-Reference-Cited by-同舟云学术

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Mild and Diazo-Free Synthesis of Trifluoromethyl-Cyclopropanes Using Sulfonium Ylides

Published:2019-03-18 Issue:7 Volume:21 Page:2265-2268
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Cyr Patrick¹^ORCID,Flynn-Robitaille Joël¹,Boissarie Patrick¹,Marinier Anne¹²³

Affiliation:

1. Medicinal Chemistry, Institute of Research in Immunology and Cancer, Université de Montréal, Montreal, QC H3C 3J7, Canada

2. Département de chimie, Faculté des Arts et Sciences, Université de Montréal, Montreal, QC H3C 3J7, Canada

3. Département de pharmacologie, Faculté de Médecine, Université de Montréal, Montreal, QC H3C 3J7, Canada

Funder

Canadian Institutes of Health Research

Fondation Marcel et Rolande Gosselin

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.9b00557

Reference43 articles.

1. The “Cyclopropyl Fragment” is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules

2. Rings in Drugs

3. Evaluation oftert-Butyl Isosteres: Case Studies of Physicochemical and Pharmacokinetic Properties, Efficacies, and Activities

4. Metabolically Stable tert-Butyl Replacement

5. Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity

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3. Taming of Furfurylidenes by Chiral Bismuth‐Rhodium Paddlewheel Catalysts. Preparation and Functionalization of Optically Active 1,1‐Disubstituted (Trifluoromethyl)cyclopropanes;Angewandte Chemie;2023-09-21

4. Taming of Furfurylidenes by Chiral Bismuth‐Rhodium Paddlewheel Catalysts. Preparation and Functionalization of Optically Active 1,1‐Disubstituted (Trifluoromethyl)cyclopropanes;Angewandte Chemie International Edition;2023-09-21

5. General and Scalable Approach to Trifluoromethyl-Substituted Cyclopropanes;J ORG CHEM;2023

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