Diversity-Oriented Synthesis of ERα Modulators via Mitsunobu Macrocyclization

Author:

Dai Chuan1234ORCID,Lian Chenshan56,Fang Huilong3,Luo Qinhong123,Huang Junrong1,Yang Min1,Yang Heng123,Zhu Lizhi123,Zhang Jinqiang4ORCID,Yin Feng56,Li Zigang56ORCID

Affiliation:

1. Department of Pharmacy, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People’s Hospital (Shenzhen Institute of Translational Medicine), Shenzhen 518035, China

2. Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen 518060, China

3. Department of Pathogenic Biology and Immunology, Xiangnan University, Chenzhou 423043, China

4. Innovative Drug Research Centre (IDRC), Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, P. R. China

5. Pingshan translational medicine centre, Shenzhen Bay Laboratory, Shenzhen 518118, P. R. China

6. State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen 518055, China

Funder

National Natural Science Foundation of China

Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions

Shenzhen Science and Technology Innovation Committee

Hunan Provincial Health Commission Scientific research project

Basic research program of China 973 program

National College Students' innovation and entrepreneurship training program

Natural Science Foundation of Guang-dong Province

Shenzhen Key Medical Discipline Construction Fund

Beijing National Laboratory of Molecular Science

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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