Cu-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of N-2,2,2-Trifluoroethylisatin Ketimines Enables the Desymmetrization of N-Arylmaleimides: Access to Enantioenriched F3C-Containing Octahydropyrrolo[3,4-c]pyrroles-Reference-Cited by-同舟云学术

Cu-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of N-2,2,2-Trifluoroethylisatin Ketimines Enables the Desymmetrization of N-Arylmaleimides: Access to Enantioenriched F₃C-Containing Octahydropyrrolo[3,4-c]pyrroles

Published:2022-05-27 Issue:22 Volume:24 Page:4052-4057
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Wang Zhen-Hua¹^ORCID,Liu Ji-Hong²,Zhang Yan-Ping¹,Zhao Jian-Qiang¹^ORCID,You Yong¹^ORCID,Zhou Ming-Qiang³,Han Wen-Yong²^ORCID,Yuan Wei-Cheng¹^ORCID

Affiliation:

1. Innovation Research Center of Chiral Drugs, Institute for Advanced Study, Chengdu University, Chengdu 610106, China

2. School of Pharmacy, Zunyi Medical University, Zunyi 563006, China

3. National Engineering Research Center of Chiral Drugs, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China

Funder

Chengdu University

Department of Science and Technology of Sichuan Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.2c01510

Reference55 articles.

1. Discovery of novel substituted octahydropyrrolo[3,4- c ]pyrroles as dual orexin receptor antagonists for insomnia treatment

2. Novel Octahydropyrrolo[3,4-c]pyrroles Are Selective Orexin-2 Antagonists: SAR Leading to a Clinical Candidate

3. Identification of a novel series of potent HCV NS5B Site I inhibitors

4. Synthesis of Spiro{pyrrolidine‐3,1′‐pyrrolo[3,4‐ c ]pyrrole} Basic Framework by Multicomponent 1,3‐Dipolar Cycloaddition

5. Molecular diversity of the three-component reaction of α-amino acids, dialkyl acetylenedicarboxylates and N-substituted maleimides

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