Direct Hydrodefluorination of CF<sub>3</sub>-Alkenes via a Mild S<sub>N</sub>2′ Process Using Rongalite as a Masked Proton Reagent-Reference-Cited by-同舟云学术

Direct Hydrodefluorination of CF₃-Alkenes via a Mild S_N2′ Process Using Rongalite as a Masked Proton Reagent

Published:2023-03-23 Issue:13 Volume:25 Page:2294-2299
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Chen Xiang-Long¹,Yang Dong-Sheng¹,Tang Bo-Cheng²,Wu Chun-Yan¹,Wang Huai-Yu¹,Ma Jin-Tian¹,Zhuang Shi-Yi¹,Yu Zhi-Cheng¹,Wu Yan-Dong¹^ORCID,Wu An-Xin¹^ORCID

Affiliation:

1. Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China

2. State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon 999077, Hong Kong SAR, China

Funder

National Natural Science Foundation of China

Higher Education Discipline Innovation Project

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.3c00645

Reference51 articles.

1. Fluorine in Pharmaceuticals: Looking Beyond Intuition

2. Fluorine in medicinal chemistry