Site-Selective Modification of Peptides via Late-Stage Pd-Catalyzed Tandem Reaction of Phenylalanine with Benzoquinone
Author:
Affiliation:
1. Key Laboratory of Catalytic Conversion and Clean Energy in Universities of Shandong Province, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P. R. China
Funder
China Postdoctoral Science Foundation
Qufu Normal University
Natural Science Foundation of Shandong Province
Shandong Province
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.3c01952
Reference50 articles.
1. Late-stage functionalization of peptides via a palladium-catalyzed C(sp3)–H activation strategy
2. Peptide therapeutics: current status and future directions
3. The Future of Peptide-based Drugs
4. Cyclic peptide drugs approved in the last two decades (2001–2021)
5. Targeting “Undruggable” Proteins: Design of Synthetic Cyclopeptides
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1. Backbone-enabled modification of peptides with benzoquinone via palladium-catalyzed δ-C(sp2)–H functionalization;Chemical Communications;2024
2. Pd-Catalyzed Picolinamide-Directed Late-Stage Chalcogenation of Tryptophan-Containing Peptides;The Journal of Organic Chemistry;2023-10-26
3. Late-Stage Diversification of Peptides via Pd-Catalyzed Site-Selective δ-C(sp2)-H Fluorination and Amination;The Journal of Organic Chemistry;2023-09-26
4. Palladium-Catalyzed Late-Stage Functionalization of Phenylalanine and Phenylalanine Derived Peptides;Synfacts;2023-09-14
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