Methionine-enabled peptide modification through late-stage Pd-catalyzed β-C(sp<sup>3</sup>)–H olefination/cyclization-Reference-Cited by-同舟云学术

Methionine-enabled peptide modification through late-stage Pd-catalyzed β-C(sp³)–H olefination/cyclization

Published:2024 Issue:61 Volume:60 Page:7942-7945
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Lu Fengjie¹,Zhang Xinyi¹,Geng Yujie¹,Wang Huihui¹,Tang Jian¹²³^ORCID

Affiliation:

1. Key Laboratory of Catalytic Conversion and Clean Energy in Universities of Shandong Province, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P. R. China

2. Zhejiang Sci-Tech University Shengzhou Innovation Research Institute, Shengzhou 312400, P. R. China

3. Zhejiang Zhongxin Fluoride Materials Co., LTD, Shangyu 312369, P. R. China

Abstract

We present a method for site-selective diversification of peptides via Pd-catalyzed β-C(sp3)–H olefination/cyclization.

Funder

Postdoctoral Research Foundation of China

Natural Science Foundation of Shandong Province

Qingchuang Talents Induction Program of Shandong Higher Education Institution

Qufu Normal University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC02739F

Reference39 articles.

1. Late-stage functionalization of peptides via a palladium-catalyzed C(sp3)–H activation strategy

2. Peptide therapeutics: current status and future directions

3. Trends in peptide drug discovery

4. Therapeutic peptides: Historical perspectives, current development trends, and future directions

5. The Future of Peptide-based Drugs

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