Semisynthetic Lipopeptides Derived from Nisin Display Antibacterial Activity and Lipid II Binding on Par with That of the Parent Compound-Reference-Cited by-同舟云学术

Semisynthetic Lipopeptides Derived from Nisin Display Antibacterial Activity and Lipid II Binding on Par with That of the Parent Compound

Published:2015-07-14 Issue:29 Volume:137 Page:9382-9389
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Koopmans Timo¹,Wood Thomas M.¹,’t Hart Peter¹,Kleijn Laurens H. J.¹,Hendrickx Antoni P. A.²,Willems Rob J. L.²,Breukink Eefjan³,Martin Nathaniel I.¹

Affiliation:

1. Department of Medicinal Chemistry & Chemical Biology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG Utrecht, The Netherlands

2. Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands

3. Membrane Biochemistry and Biophysics Group, Department of Chemistry, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Utrecht University

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.5b04501

Reference46 articles.

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3. Prospects for new antibiotics: a molecule-centered perspective

4. Antibiotics: A New Hope

5. Drugs for bad bugs: confronting the challenges of antibacterial discovery

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