Trypanosoma cruzi Trans-sialidase Operates through a Covalent Sialyl−Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile-Reference-Cited by-同舟云学术

Trypanosoma cruzi Trans-sialidase Operates through a Covalent Sialyl−Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile

Published:2003-05-30 Issue:25 Volume:125 Page:7532-7533
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Watts Andrew G.¹,Damager Iben¹,Amaya Maria L.¹,Buschiazzo Alejandro¹,Alzari Pedro¹,Frasch Alberto C.¹,Withers Stephen G.¹

Affiliation:

1. Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, B.C., Canada V6T 1Z1, Unite de Biochemie Structurale, Institut Pasteur, 25 rue du Dr. Roux, 75724 Paris, France, and Instituto de Investigaciones Biotechnologicas-Universidad Nacional de San Martin, CC 30, 1650 San Martin, Argentina

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja0344967

Reference13 articles.

1. Identification of the gene(s) coding for the trans-sialidase of Trypanosoma cruzi.

2. The trans -sialidase from the african trypanosome Trypanosoma brucei

3. Functional Diversity in the Trans-sialidase and Mucin Families in Trypanosoma cruzi

4. The High Resolution Structures of Free and Inhibitor-bound Trypanosoma rangeli Sialidase and its Comparison with T.cruziTrans-sialidase

5. The Crystal Structure and Mode of Action of Trans-Sialidase, a Key Enzyme in Trypanosoma cruzi Pathogenesis

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