Pharmacometabonomic Investigation of Dynamic Metabolic Phenotypes Associated with Variability in Response to Galactosamine Hepatotoxicity-Reference-Cited by-同舟云学术

Pharmacometabonomic Investigation of Dynamic Metabolic Phenotypes Associated with Variability in Response to Galactosamine Hepatotoxicity

Published:2012-03-02 Issue:4 Volume:11 Page:2427-2440
ISSN:1535-3893
Container-title:Journal of Proteome Research
language:en
Short-container-title:J. Proteome Res.

Author:

Coen Muireann¹,Goldfain-Blanc Françoise²,Rolland-Valognes Gaëlle³,Walther Bernard⁴,Robertson Donald G.⁵,Holmes Elaine¹,Lindon John C.¹,Nicholson Jeremy K.¹

Affiliation:

1. Biomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, United Kingdom

2. Toxicology, Biologie Servier, 905 Route de Saran, 45520 Gidy, France

3. Molecular Pharmacology and Pathophysiology, Institut de Recherches Servier, 125 Chemin de Ronde, 78290 Croissy Sur Seine, France

4. DMPK, Technologie Servier, 2527 Rue Eugène Vignat, Orleans 45000, France

5. Research and Development, Bristol-Myers Squibb, Princeton, New Jersey, United States

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/pr201161f

Reference78 articles.

1. Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development

2. Can the pharmaceutical industry reduce attrition rates?

3. Incidence of Adverse Drug Reactions in Hospitalized Patients

4. Galactosamine hepatitis: Key role of the nucleotide deficiency period in the pathogenesis of cell injury and cell death

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