Quinazolinone Derivatives as Orally Available Ghrelin Receptor Antagonists for the Treatment of Diabetes and Obesity-Reference-Cited by-同舟云学术

Quinazolinone Derivatives as Orally Available Ghrelin Receptor Antagonists for the Treatment of Diabetes and Obesity

Published:2007-09-21 Issue:21 Volume:50 Page:5202-5216
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Rudolph Joachim¹,Esler William P.¹,O'Connor Stephen¹,Coish Philip D. G.¹,Wickens Philip L.¹,Brands Michael¹,Bierer Donald E.¹,Bloomquist Brian T.¹,Bondar Georgiy¹,Chen Libing¹,Chuang Chih-Yuan¹,Claus Thomas H.¹,Fathi Zahra¹,Fu Wenlang¹,Khire Uday R.¹,Kristie James A.¹,Liu Xiao-Gao¹,Lowe Derek B.¹,McClure Andrea C.¹,Michels Martin¹,Ortiz Astrid A.¹,Ramsden Philip D.¹,Schoenleber Robert W.¹,Shelekhin Tatiana E.¹,Vakalopoulos Alexandros¹,Tang Weifeng¹,Wang Lei¹,Yi Lin¹,Gardell Stephen J.¹,Livingston James N.¹,Sweet Laurel J.¹,Bullock William H.¹

Affiliation:

1. Departments of Chemistry Research, Metabolic Disorders Research, and Research Technologies, Bayer Pharmaceuticals Corporation, 400 Morgan Lane, West Haven, Connecticut 06516

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070071%2B

Reference42 articles.

1. Drugs on the horizon for diabesity

2. Biological, Physiological, Pathophysiological, and Pharmacological Aspects of Ghrelin

3. Roles for ghrelin in the regulation of appetite and body weight

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