Discovery of Novel 1,2,4-Thiadiazole Derivatives as Potent, Orally Active Agonists of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P1)-Reference-Cited by-同舟云学术

Discovery of Novel 1,2,4-Thiadiazole Derivatives as Potent, Orally Active Agonists of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P1)

Published:2012-04-20 Issue:9 Volume:55 Page:4286-4296
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ren Feng¹,Deng Guanghui¹,Wang Hailong¹,Luan Linbo¹,Meng Qinghua¹,Xu Qiongfeng¹,Xu Heng¹,Xu Xuesong¹,Zhang Haibo¹,Zhao Baowei¹,Li Chengyong¹,Guo Taylor B.¹,Yang Jiansong¹,Zhang Wei¹,Zhao Yonggang¹,Jia Qiantao¹,Lu Hongtao¹,Xiang Jia-Ning¹,Elliott John D.¹,Lin Xichen¹

Affiliation:

1. GlaxoSmithKline, R&D China, No. 3 Building, 898 Halei Road, Zhangjiang Hi-Tech Park, Pudong, Shanghai 201203, PRC

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2016107

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4. FTY720: Sphingosine 1-Phosphate Receptor-1 in the Control of Lymphocyte Egress and Endothelial Barrier Function

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