Development of a Potential High-Throughput Workflow to Characterize Sites of Bioconjugation by Immuno-Affinity Capture Coupled to MALDI-TOF Mass Spectrometry-Reference-Cited by-同舟云学术

Development of a Potential High-Throughput Workflow to Characterize Sites of Bioconjugation by Immuno-Affinity Capture Coupled to MALDI-TOF Mass Spectrometry

Published:2012-12-12 Issue:1 Volume:24 Page:53-62
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Dai Lan¹,Preston Ryan¹,Bacica Michael¹,Kinhikar Arvind¹,Bolaños Ben²,Murphy Robert E.¹

Affiliation:

1. Department of Analytical Sciences, CovX, Pfizer Worldwide Research and Development, 9381 Judicial Drive, Suite 200, San Diego, California 92121, United States

2. Department of Oncology Platform Chemistry, Pfizer Worldwide Research and Development, 10770 Science Center Drive, La Jolla, California 92121, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/bc300413c

Reference32 articles.

1. Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

2. Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

3. Chemically programmed antibodies: Endothelin receptor targeting CovX-Bodies™

4. Chemical generation of bispecific antibodies

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Click Bioconjugation: Modifying Proteins Using Click‐Like Chemistry;ChemBioChem;2022-05-18

2. Biosensor surface functionalization by a simple photochemical immobilization of antibodies: experimental characterization by mass spectrometry and surface enhanced Raman spectroscopy;The Analyst;2019

3. Mass spectrometry characterization of DOTA-Nimotuzumab conjugate as precursor of an innovative β − tracer suitable in radio-guided surgery;Journal of Pharmaceutical and Biomedical Analysis;2018-07

4. Proximity hybridization triggered rolling-circle amplification for sensitive electrochemical homogeneous immunoassay;The Analyst;2017

5. Preclinical and clinical formulation studies;High-Throughput Formulation Development of Biopharmaceuticals;2017