Discovery of Multifold Modified Sialosides as Human CD22/Siglec-2 Ligands with Nanomolar Activity on B-Cells
Author:
Affiliation:
1. G3-BioTec, 69207 Sandhausen, Germany
2. Chair of Genetics, Department of Biology, University of Erlangen, 91058 Erlangen,Germany
3. Biochemistry Center, University of Heidelberg, 69120 Heidelberg, Germany
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/cb400952v
Reference52 articles.
1. Sialic acid-specific lectins: occurrence, specificity and function
2. Functional groups of sialic acids involved in binding to siglecs (sialoadhesins) deduced from interactions with synthetic analogues
3. Structure-Guided Design of Sialic Acid-Based Siglec Inhibitors and Crystallographic Analysis in Complex with Sialoadhesin
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