Asymmetric Synthesis of 4,4-Disubstituted-2-Imidazoli-dinones: Potent NK1 Antagonists-Reference-Cited by-同舟云学术

Asymmetric Synthesis of 4,4-Disubstituted-2-Imidazoli-dinones: Potent NK1 Antagonists

Published:2003-10-23 Issue:23 Volume:5 Page:4249-4251
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Reichard Gregory A.¹,Stengone Carmine¹,Paliwal Sunil¹,Mergelsberg Ingrid¹,Majmundar Sapna¹,Wang Cheng¹,Tiberi Robert¹,McPhail Andrew T.¹,Piwinski John J.¹,Shih Neng-Yang¹

Affiliation:

1. Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, Werthenstein Chemie AG, Industriestrasse, CH-6105 Schachen, Switzerland, and Department of Chemistry, P.M. Gross Chemical Laboratory, Duke University, Durham, North Carolina 27708

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol030104p

Reference8 articles.

1. Shih, N.Y.; Shue, H.J.; Reichard, G. A.; Paliwal, S.; Blythin, D. J.; Piwinski, J. J.; Xiao, D.; Chen, X. PCT Int. Appl. WO 0144200, 2001.

2. Acyclic NK1 antagonists: Replacements for the benzhydryl group.

3. Enantioselective synthesis of α-branched α-amino acids with bulky substituents

4. Selektive Umfunktionalisierung der terminalen Amidgruppe offenkettiger Polyamidevia2-Oxazolin-5-one als Zwischenstufen. Vorläufige Mitteilung

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