Cβ-Selective Aldol Addition of d-Threonine Aldolase by Spatial Constraint of Aldehyde Binding-Reference-Cited by-同舟云学术

Cβ-Selective Aldol Addition of d-Threonine Aldolase by Spatial Constraint of Aldehyde Binding

Published:2021-05-28 Issue:12 Volume:11 Page:6892-6899
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Park Sung-Hyun¹²,Seo Hogyun³⁴,Seok Jihye³,Kim Haseong¹²,Kwon Kil Koang¹,Yeom Soo-Jin⁵,Lee Seung-Goo¹²^ORCID,Kim Kyung-Jin³^ORCID

Affiliation:

1. Synthetic Biology and Bioengineering Research Center, Korea Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea

2. Department of Biosystems and Bioengineering, KRIBB School, University of Science and Technology (UST), Daejeon 34113, Republic of Korea

3. School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, KNU Institute for Microorganisms, Kyungpook National University, Daegu 41566, Republic of Korea

4. Pohang Accelerator Laboratory, Pohang University of Science and Technology, Pohang 37673, Republic of Korea

5. School of Biological Sciences and Technology, Chonnam National University, Yongbong-ro 77, Gwangju 61186, Republic of Korea

Funder

Korea Research Institute of Bioscience and Biotechnology

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscatal.1c01348

Reference34 articles.

1. Engineering aldolases as biocatalysts

2. Expanding the reaction space of aldolases using hydroxypyruvate as a nucleophilic substrate

3. Recent progress in stereoselective synthesis with aldolases

4. Tuning and Switching Enantioselectivity of Asymmetric Carboligation in an Enzyme through Mutational Analysis of a Single Hot Spot

5. Building Bridges: Biocatalytic C–C-Bond Formation toward Multifunctional Products

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