Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions-Reference-Cited by-同舟云学术

Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions

Published:2019-01-07 Issue:2 Volume:9 Page:1503-1513
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Biewenga Lieuwe¹,Saravanan Thangavelu¹,Kunzendorf Andreas¹,van der Meer Jan-Ytzen¹,Pijning Tjaard²,Tepper Pieter G.¹,van Merkerk Ronald¹,Charnock Simon J.³,Thunnissen Andy-Mark W. H.⁴,Poelarends Gerrit J.¹^ORCID

Affiliation:

1. Department of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands

2. Structural Biology Group, Groningen Institute of Biomolecular Sciences and Biotechnology, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands

3. Prozomix Ltd., Station Court, Haltwhistle, Northumberland NE49 9HN, United Kingdom

4. Molecular Enzymology Group, Groningen Institute of Biomolecular Sciences and Biotechnology, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands

Funder

H2020 Industrial Leadership

H2020 European Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acscatal.8b04299

Reference34 articles.

1. Chemoenzymatic Asymmetric Synthesis of Pregabalin Precursors via Asymmetric Bioreduction of β-Cyanoacrylate Esters Using Ene-Reductases